In Shakespeare’s play Hamlet, the main character wonders: “to be or not to be? This is the question”, in order to know his real nature. Today, the international opinion is asked to solve a similar but more delicate dilemma about Sakineh Mohammadi Ashtiani: “ To be her killer or not to be?”. The answer will show the real nature of the human race. Sakineh, an Iranian woman, was condemned to jail and lapidation in 2006 because of her immoral conduct. Her guilt was of having kept a love relationship with two men, while married. As a consequence, she was convicted to 99 lashes, by the Court of Tabriz. Soon after she was suspected of having played a role in the murder of her husband, killed by one of her lovers. The double charges pending on her, led Sakineh to the capital punishment by lapidation. In spite of the decision of the Supreme Court of Iran, Sakineh was not executed on May 2007, thanks to the mediation of the Ayatollah Ali Kahmenei. The international society paid more attention to Sakineh’s destiny since she had confessed her double crime in august 2010. According to many she was forced to say that, after being tortured the days before. Since then a collective mobilization has been working in order to stop the capital punishment she was intended to: hanging. As usual, Iran is deaf to the condemnation of the international community, stating that it is just manipulating the situation to blame its government. Beyond the international controversy, the case of Sakineh should finally demonstrate whether men are respectful of human rights or not. The hamletic question to fight is clear and loud: “To kill or not to kill Sakineh?”. It also sounds clear and loud that it is not just an existential question but a matter of global responsibility